General Information

  • ID:  hor003795
  • Uniprot ID:  P84353
  • Protein name:  Periviscerokinin-2
  • Gene name:  NA
  • Organism:  Sarcophaga bullata (Grey flesh fly) (Neobellieria bullata)
  • Family:  Periviscerokinin family
  • Source:  Animal
  • Expression:  Dorsal ganglionic sheath of fused ventral nerve cord.
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Neobellieria (subgenus), Sarcophaga (genus), Sarcophaginae (subfamily), Sarcophagidae (family), Oestroidea (superfamily), Calyptratae, Schizophora, Cyclorrhapha, Eremoneura, Muscomorpha (infraorder), Brachycera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  AGLLVYPRL
  • Length:  9(1-9)
  • Propeptide:  AGLLVYPRL
  • Signal peptide:  NA
  • Modification:  T9 Leucine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic activity
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003795_AF2.pdbhor003795_ESM.pdb

Physical Information

Mass: 114412 Formula: C48H80N12O11
Absent amino acids: CDEFHIKMNQSTW Common amino acids: L
pI: 9.35 Basic residues: 1
Polar residues: 2 Hydrophobic residues: 5
Hydrophobicity: 106.67 Boman Index: 649
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 173.33
Instability Index: 584.44 Extinction Coefficient cystines: 1490
Absorbance 280nm: 186.25

Literature

  • PubMed ID:  14706527
  • Title:  Mass Spectrometric Analysis of Putative Capa-Gene Products in Musca Domestica and Neobellieria Bullata